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Other Comments:
According to my opinion, the manuscript represents a satisfactory review on the pharmacological activities of Sandoricum koetjape. However, I suggest some modifications:
1. pg 2, 'Natyral products and cancer treatment', the authors should better specify the ecological role of secondary metabolites (for plant), in oppositio to their biological activities relevant to human health ('as a result' is misleading). Furthemore, I would add phenylpropanoids to the list of secondary metabolites.
2. I would introduce a review on limonoids, because of their abundance in S. koetjape, such as that of Roy and Saraf 2006, Limonoids, overview of significant bioactive triterpenes distributed in plants kingdom, Biol Pharm Bull, as well as the reference Pancharoen et al., 2009, Two new limonoids from the leaves of Sandoricum koetjape, Nar Prod Res 23(1):10-16.
3. A number of typing and diction erroer are present in the text, particularly in pg 4 and also in References.
4. Tables 1 and 2 have been exchamged; in tab 1 (that should be the tab 2) there is 'Sandricum' and in tab 2 (that should be the tab 1) there is 'triterpenids'.
5. In the text, fig. 1 and 2 should be reported, instead of 'Plate 1.1' and 'Figure 1.3' (pg 3)
6. The acronym MIC (minimun inhibitory concnetration) should be written in extenso
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Competing interests:
no
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Invited by the author to review this article? :
No -
Have you previously published on this or a similar topic?:
Yes
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References:
Iriti, M.; Faoro, F. Bioactivity of grape chemicals for human health. Nat. Prod. Commun., 2009, 4, 611-634. -
Experience and credentials in the specific area of science:
Biological activity of grape chemicals
- How to cite: Iriti M .The pharmacological properties of terpenoids from 'Sandronicum koetjape'[Review of the article 'The Pharmacological Properties Of Terpenoids From Sandoricum Koetjape ' by Abdul Majid A].WebmedCentral 2011;1(12):WMCRW00253
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Other Comments:
General comment on referring some patents as well.... there are many of them focussed on Terpenoids
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Competing interests:
None
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Invited by the author to review this article? :
Yes -
Have you previously published on this or a similar topic?:
No
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References:
None -
Experience and credentials in the specific area of science:
Yes
- How to cite: Arora S .Sandoricum Koetjape[Review of the article 'The Pharmacological Properties Of Terpenoids From Sandoricum Koetjape ' by Abdul Majid A].WebmedCentral 2011;1(12):WMCRW00236
The “Influence of medicinal plants on diseases treatment” section can be written in more concise way and I think the title does not reflect what is really discussed by the author
From my opinion the author need to introduce more information regarding the mechanism of action in the malignant cell especially the DNA polymerase inhibition story.
One attractive point mentioned in this review is the anti-bacterial activity and more information and scientific finding will add a better value for the review.
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i have beed working on plant extracts activity agianst cancer for a while and some publications will come out soon