My opinion
 

By Dr. Deepak Gupta
Corresponding Author Dr. Deepak Gupta
Self, - United States of America
Submitting Author Dr. Deepak Gupta
PUBLIC HEALTH

Nobel, Masks, Pill

Gupta D. My Personal Nobel Panacea: Curative Masks And Peacekeeping Pill. WebmedCentral PUBLIC HEALTH 2021;12(4):WMC005696

This is an open-access article distributed under the terms of the Creative Commons Attribution License(CC-BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Submitted on: 01 Apr 2021 11:13:33 PM GMT
Published on: 06 Apr 2021 03:20:34 AM GMT

My opinion


I will outrightly share however outrageous of a dream I have always had. I had a dream that one day I will hold or hand Nobel. However, I never chose a path to specialization that could have fulfilled that dream. Yet, I had an impossible dream. Although I have a dream that may never be fulfilled, there is a reality that may always get realized because there are some theories which should be timely and harmlessly promoted globally.

Masks As Cure


One theory simply explores and explains the “therapeutic” role of masks themselves thus postulating masks themselves as non-pharmacological antidote against SARS-CoV-2 [1]. As an anesthesiologist, it is ironic that it all started more than a decade ago in 2009 when my natural aversion to wearing masks led me to explore why it is so [2-3]. Then a decade later, I flipped when it came up in my discussions with my close friend as well as long-time associate who introduced the role of ambient humidity against flu to me. This was in 2019, just before COVID-19 era was dawning. Then, COVID-19 pandemic reached the shores of America. On January 11, 2020, scientists theorized COVID-19 vaccine within days [4] based on the disclosed genetic code of SARS-CoV-2 because they had preemptively thought and prepared tool to develop vaccine waiting just for SARS-CoV-2 genetic code’s input. Similarly, on April 24, 2020, I had shared my interpretation about “therapeutic” masks within a day [5] based on Department of Homeland Security, Science and Technology, Under Secretary, William N. Bryan, disclosing scientific results [6] regarding hot and humid climates acting against SARS-CoV-2 because I had preemptively thought [7] and prepared tool to promote masks as “cure” waiting just for encouraging laboratory data. Although it seems prudent to allow almost a year [8] to prove theorized vaccines’ efficacy and safety, it seems imprudent to me that the theory of “therapeutic” masks has not caught the imagination of the world yet until now [9-11] because it has been my strong belief since the dawn of COVID-19 pandemic that masks may be acting in a triplet role for the mask wearers when (a) filtering most if not all pathogens to prevent contagion reaching to them, (b) allowing rare but some of pathogens to induce manageable immunogenicity in them, and (c) always creating hot and humid micro-environments to inactivate vulnerable pathogens which are already inside them [12-14]. Masks may be therapeutic by not only "hydrating the respiratory tract" [11] but also "heating the respiratory tract" [15-16] because it is my opinion that just like dry heat may be poorly tolerable, cold mist may be poorly effective even when the modern invention of cold misted air may seem to have overtaken the ancient philosophy of warm misted air in the current school of thought as well as usage by population. Exploration to document therapeutic potential of masks in global preparations may be futuristic against current and future airborne/droplet transmission-based pathogens inducing endemic clusters, epidemics and pandemics because human airways will always be physiologically colder than their blood thus therein favoring “cold” pathogens which may evolve to prefer airborne/droplet transmission via colder human airways and in turn always remaining vulnerable to non-pharmacological hot and humid [17-18] in-mask micro-environments.

Therefore, I am hoping that the readers take a look at my thoughts once again and have a hearty laugh on behalf of my published theories [19-20]. In the process, I am hoping that I along with the humanity can have the final laugh if masks can get christened as the “cure” against the “cold” viruses, now onwards and for the times to come. SARS-CoV-2 may neither be the first nor be the last inflicting pains to our urbanized globalized world. Thus, unlike condoms [21] just barricading to protect our sexual lives not only against HIV but also against all STDs, humanity may have to embrace masks as “cure” (not just as therapeutic goods in legal terms [22-23]) to protect our social lives not only against SARS-CoV-2 but also against all “cold” viruses to be implicated in global pandemics.  

Nuclear Pill Feminism


Real life itself unravels the biggest joke. Although it may not seem to be a laughing matter, it has the potential to make us a laughing stock because cultural reservations may sometimes obscure Nobel to consider an avenue for peace prize. That avenue is Nuclear “Pill” Feminism with too many mothers of second-wave feminism [24] and too many fathers of modern pill [25] but no takers for the credit to nuclear power. If President Franklin D. Roosevelt was right to “fear the fear” [26], it seems like the fear of apocalyptic war forced humanity to invent pill as a counter-mechanism to sustain peace within the sea of humanity at the top of food chain. Absence of war in itself is not peace unless usable resources remain appropriated to match needs of their consumers. Although humans have created opportunities by recklessly borrowing from their indebted descendants to falsely sustain peace, humanity must actually thank pill for the actual peace by non-violently limiting the expanding vastness of its sea; this is in contrast to inter/intra-species [27]-specific prey-predator balancing in the violent wild. However, pill itself could not have reached the targeted torchbearers of peace without the second-wave of feminism actively and fanatically promoting it. Essentially, fearing the fear of nuclear power created peace [28] with sustenance of peace warranting creation of pill to humanely restrict growth of humanity. However, the created pill needed prowess of feminism to deep-root it into modern psyche and its way of living so that the living can go on living for a longer time without waging wars for their overlapping and conflicting needs in the face of declining usability of the contracting pool of global resources [29].

If the readers are not even smiling yet, they should ponder the following questions:

  • Can’t non-violence ever create violence [30] unless peace never creates war?
  • Don’t fertility rates decrease during the wars to increase after the end of wars [31]?
  • Doesn’t pill have anything to do with humanity not meeting the population explosion projections [32] made after the last world war?
  • Isn’t anti-pill ideology/stand complemented by pro-war ideology/stand [33]?
  • Doesn’t rush-hour highway decongestion analogy [34] need decreased numbers who are entering and/or increased numbers who are exiting until and unless available space allowing increasing the numbers of new highways or increasing the numbers of lanes in the existing highways?
  • Isn’t Nuclear “Pill” Feminism being pro-life by being pro-choice even before the time [35] when the dilemmatic choice has to be made about what denotes life at what point in the existence?
  • Aren’t the other pills themselves driving the pill-popping world towards auto-(self)-cannibalism mode without knowing whether this is the naïve beginning or the desperate end wherein the healing question to humanely control overpopulation may be constantly eluding the Fisher King [36]?

This is nature’s cruel joke and none is laughing because joke is on us all unless we felicitate Nuclear “Pill” Feminism for creating more (technology) work and less (human) workers to ensure long term non-warring peace while accommodating the imminent artificial intelligence-induced downsizing [37] before the peaceful transition of power [38] from humanity to artificial intelligence happens at the top of food chain [39].

Conclusion


Summarily, as thoughts and theories will keep on flowing from mind, I will continue to have my Nobel dream and nurture its improbable fulfillment therein.

References


  1. Gupta D. "Therapeutic" facemasks. Med Hypotheses. 2020;143:109855. https://doi.org/10.1016/j.mehy.2020.109855
  2. Gupta D. Love Hate Love Hate Love Story. https://twitter.com/search?q=andgandg%20Love%20Hate%20Love%20Hate%20Love%20Story& amp;src=typed_query&f=live
  3. Gupta D. Transnasal cooling: a Pandora's box of transnasal patho-physiology. Med Hypotheses. 2011;77(2):275-277. https://doi.org/10.1016/j.mehy.2011.04.034
  4. Business Insider. Moderna's groundbreaking coronavirus vaccine was designed in just 2 days https: //www.businessinsider.com/moderna-designed-coronavirus-vaccine-in-2-days-2020-11
  5. Gupta D. https://twitter.com/andgandg/status/1 253804454559784961
  6. YouTube. Virus does less well in sunlight and warm, humid conditions: DHS. https://www.youtube.com/watch?v=E94pqy2rB7g
  7. Gupta D. Therapeutic. https://tw itter.com/search?q=andgandg%20therapeutic&src=typed_query&f=live
  8. Engel R. https://twitter.com/OARichardEn gel/status/1326900231825461255
  9. Yong SJ. If Coronavirus Thrive in Cold Noses, Then Keeping It Warm May Help:An unconventional view of facemasks. https://medium.com/microbial-instincts/if-coronavirus-thrive-in-cold-noses- then-keeping-it-warm-may-help-5863fc2a7bdb
  10. Gupta D. https://twitter.com/andgandg/status/1 327352035906359300
  11. Courtney JM, Bax A. Hydrating the respiratory tract: an alternative explanation why masks lower severity of COVID-19 [published online ahead of print, 2021 Feb 12]. Biophys J. 2021;S0006-3495(21)00116-8. https://doi.org/10.1016/j.bpj.2021.02.002
  12. Gupta D. Until Advancing Age Gets Reversed With A Pinch Of Salt, Usage Duration Of Mask Trinity As Universal Precaution Against Discrimination. WebmedCentral PUBLIC HEALTH 2020;11:WMC005670. http://www.webmedcentral.com/article_view/5670
  13. Gupta D. Investigate In-Mask Temperature As A Surrogate Indicator Of Potentially "Therapeutic" Nasopharyngeal Temperature Denoting Masks' Therapeutic Efficiency To Complement Masks' Filtration Efficiency Against SARS-CoV-2 And Its Variants. WebmedCentral OTORHINOLARYNGOLOGY 2021;12:WMC005692. http://www.webmedcentral.com/article_view/5692
  14. Gupta D. Worth Investigating: Sunbathing (Sunfacial) With Masks On (SUMA) For Cleansing "Cold" Viruses. WebmedCentral INFECTIOUS DISEASES 2020;11:WMC005672. http://www.webmedcentral.com/article_view/5672
  15. Foxman EF, Storer JA, Fitzgerald ME, Wasik BR, Hou L, Zhao H, Turner PE, Pyle AM, Iwasaki A. Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells. Proc Natl Acad Sci USA 2015;112:827-832. https://www.pnas.org/content/112/3/827
  16. Gallo O, Locatello LG, Mazzoni A, Novelli L, Annunziato F. The central role of the nasal microenvironment in the transmission, modulation, and clinical progression of SARS-CoV-2 infection. Mucosal Immunol 2021;14:305-316. https://www.nature.com/articles/s41385-020 -00359-2
  17. Department of Homeland Security: Science and Technology. 2020. Estimated Airborne Decay of SARS-CoV-2 (virus that causes COVID-19) under a range of temperatures, relative humidity, and UV index. https://www.dhs.gov/scien ce-and-technology/sars-airborne-calculator .
  18. 95.3 WBCKFM, Townsquare Media, Inc. 2020. Can sunlight or UV light kill the COVID-19 virus; it appears so. https://wbckfm.com/can-sunlight-or-uv-light-kill-the-covid-19-virus-it-appears-so/
  19. Gupta D. Living with in-mask micro-climate. Med Hypotheses. 2020;144:110010. https://doi.org/10.1016/j.mehy.2020.110010
  20. Gupta D. Does mask use affect the quantitative severe acute respiratory syndrome coronavirus 2 load in the nasopharynx? J Pediatr. 2021 Jan;228:314. https://doi.org/10.1016/j.jpeds.2020.09.050
  21. WebMD. Guide to Spermicide. https://www.webmd.com/sex/b irth-control/birth-control-spermicides
  22. Therapeutic Goods Administration cracks down on COVID-19 related breaches. https://w ww.lexology.com/library/detail.aspx?g=bbdf4795-c5c5-4724-8356-8d33f24a68b6
  23. Face masks and COVID-19. https://www.tga.gov.au/face-masks-and-covid-19
  24. Wikipedia. Second-wave feminism. https://en.wikipedia.org/wiki/Second-wave_ feminism
  25. Wikipedia. Combined oral contraceptive pill: History. https://en.wikipedia.o rg/wiki/Combined_oral_contraceptive_pill#History
  26. History Matters. “Only Thing We Have to Fear Is Fear Itself”: FDR’s First Inaugural Address. http://historymatters.gmu.edu/d/5057/   
  27. Weiler N. Do big carnivores practice birth control? https://www. sciencemag.org/news/2015/02/do-big-carnivores-practice-birth-control
  28. Harari YN. https://www.goodreads.com/quotes/9476557-nuclear-weapons-have-turned-war-between-superpow ers-into-a-mad
  29. Gupta D. Does Being Child-Free While Dying-Mean To Eventually Eco-Decompose Preemptively Palliate The Climate Emergency?. WebmedCentral ENVIRONMENTAL MEDICINE 2020;11(12):WMC005669. www.webmedcentral.com/article_view/5669
  30. Nicholasen M. Nonviolent resistance proves potent weapon. https://news.harvard.edu/gazette/story/2019/02/why-nonviolent- resistance-beats-violent-force-in-effecting-social-political-change/
  31. Barnier B. Baby Boomer. https://www.investopedia.com/terms/b/bab y_boomer.asp
  32. Lam D. How the world survived the population bomb: lessons from 50 years of extraordinary demographic history. Demography. 2011;48(4):1231-1262. https://doi.org/10.1007/s13524-011-0070-z
  33. The New York Times. Are Republicans ‘Pro-Life’ Beyond Abortion? https://www.nyti mes.com/2019/06/06/opinion/letters/republicans-abortion.html
  34. Rosen A. What Really Causes Traffic Congestion? https://bklyner.com /what-really-causes-traffic-congestion-sheepshead-bay/
  35. Princeton. Life Begins at Fertilization. https://www.princeton.edu/~pro life/articles/embryoquotes2.html
  36. The Fisher King’s Question. https://quinncreati ve.wordpress.com/2014/08/12/the-fisher-kings-question/
  37. Nova A. Amid the coronavirus pandemic, many companies could replace their workers with robots. https://www.cnbc.com/2020/06/06/how-companies-plan-to-hire-robots-after-coronavirus-layoffs.html
  38. Gupta D, Kumar S. Artificial Intelligence And Redundant Specialties. WebmedCentral MEDICAL ROBOTICS 2020;11(2):WMC005605. www.webmedcentral.com/article_view/5605
  39. Gupta D. Robohumans. http://pageturn.vpdeman dcreationservices.com/DMN/4Q20/index.html#p=10

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